Therapeutic Areas · 中文
Immune-mediated disease
where we focus
An immune system that attacks the body · fails to clear a pathogen · or is evaded by a tumor
one engine built for the immune system designed to address all three
Immunity that attacks the self
Autoimmune
We design therapeutics against the validated drivers of autoimmune inflammation — the deepest part of our target map and data.
Rheumatoid arthritis · Systemic lupus erythematosus · Sjögren’s · Systemic sclerosis · Vasculitis · Inflammatory bowel disease (Crohn’s, ulcerative colitis) · Psoriasis & psoriatic arthritis · Ankylosing spondylitis · Multiple sclerosis · Myasthenia gravis · Type 1 diabetes
Immunity that fails to clear
Chronic infection
The same immune-design engine, turned to infections the immune system cannot resolve on its own — restoring or redirecting the response.
Chronic viral hepatitis (HBV) · HIV · Persistent / latent viral infection · Infection-driven immune exhaustion
Immunity that is evaded
Immuno-oncology
Making immunologically “cold” tumors visible and targetable. Our lead program is a cyclic-peptide radioligand for pancreatic cancer.
Lead: Pancreatic cancer · Immunologically cold solid tumors · Checkpoint-resistant cancers
How to read this
One engine · many targets
honest about stage
Autoimmune and immuno-oncology are where our engine and data are strongest today; chronic infection is an extension of the same engine. Disease areas reflect where our design engine and proprietary data are deepest; target mechanisms are drug-blind rediscoveries from a human-genetics-anchored cross-disease analysis. Programs are discovery-stage unless marked as lead.